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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAE1
All Species:
4.55
Human Site:
S136
Identified Species:
7.69
UniProt:
Q13564
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13564
NP_001018169.1
534
60246
S136
T
Q
L
P
E
S
T
S
L
R
L
A
D
V
L
Chimpanzee
Pan troglodytes
XP_001159531
534
60179
S136
T
Q
L
P
E
S
T
S
L
R
L
A
D
V
L
Rhesus Macaque
Macaca mulatta
XP_001085059
534
60247
L136
T
Q
L
P
E
S
T
L
L
R
L
A
D
V
L
Dog
Lupus familis
XP_852003
534
60357
L136
T
Q
L
P
E
S
T
L
L
R
L
A
D
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBW6
534
60255
L136
T
Q
L
L
E
S
T
L
L
R
L
A
D
V
L
Rat
Rattus norvegicus
Q9Z1A5
534
60364
L136
T
Q
L
L
E
S
T
L
L
R
L
A
D
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505632
525
59197
L127
T
Q
L
S
E
S
T
L
L
H
L
A
E
I
L
Chicken
Gallus gallus
Q5ZIE6
535
60465
V137
T
Q
L
S
E
S
T
V
L
R
L
A
E
L
L
Frog
Xenopus laevis
Q6NTW6
533
60607
L135
T
Q
L
P
E
S
T
L
L
R
L
A
E
T
L
Zebra Danio
Brachydanio rerio
Q7SXP2
533
60386
C135
V
Q
L
P
E
S
T
C
L
R
L
G
A
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTE9
524
58698
L141
S
N
L
N
E
Q
T
L
L
L
L
A
E
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18217
541
60764
D133
A
N
Q
N
E
E
I
D
T
T
F
A
K
V
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42744
540
60016
M147
T
Q
L
V
E
D
S
M
L
K
L
D
R
I
C
Baker's Yeast
Sacchar. cerevisiae
Q12059
462
52834
L116
I
G
E
Q
T
A
M
L
D
L
N
E
I
R
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
97.7
N.A.
97
96.8
N.A.
82.7
83.9
78.8
73
N.A.
45.1
N.A.
37.7
N.A.
Protein Similarity:
100
99.6
99.4
98.8
N.A.
98.6
98.3
N.A.
91.1
93
89.6
85.9
N.A.
64.2
N.A.
55.4
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
66.6
73.3
80
73.3
N.A.
46.6
N.A.
26.6
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
80
86.6
86.6
73.3
N.A.
60
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.8
25.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.7
46.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
0
0
79
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
8
0
8
8
0
0
8
43
0
0
% D
% Glu:
0
0
8
0
93
8
0
0
0
0
0
8
29
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
0
8
15
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
0
0
86
15
0
0
0
58
86
15
86
0
0
8
86
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
15
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
43
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
79
8
8
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
65
0
0
8
15
8
% R
% Ser:
8
0
0
15
0
72
8
15
0
0
0
0
0
0
0
% S
% Thr:
72
0
0
0
8
0
79
0
8
8
0
0
0
8
0
% T
% Val:
8
0
0
8
0
0
0
8
0
0
0
0
0
58
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _